Abacavir Sulfate


Catalogue number: A105000
Chemical name: Abacavir Sulfate
Synonyms: (1S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol Sulfate; Ziagen; Abacavir - In House Impurity; Abacavir Impurities; Abacavir Intermediates
Impurity: Abacavir - In House Impurity
CAS Number: 188062-50-2
Alternate CAS #: free base: 136470-78-5
Molecular form.: C₂₈H₃₈N₁₂O₆S
Appearance: White to Off-White Solid
Melting Point: 213 - 214°C (dec.)
Mol. Weight: 670.74
Storage: -20°C Freezer, Under inert atmosphere
Solubility: Water, Methanol (Sparingly)
Stability: No Data Available
Category: Inhibitors, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: Abacavir Sulfate (Abacavir - In House Impurity) is a carbocyclic 2’-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.
Dangerous Goods Info: NA
References:


All Products are stable to be shipped at room temperature, unless otherwise specified.
MSDS: A105000.pdf
Keywords: Buy 188062-50-2 | Purchase 188062-50-2 | Order 188062-50-2 | 188062-50-2 supplier | 188062-50-2 manufacturer | 188062-50-2 distributor | 188062-50-2 cost

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  Pack size Price(USD)
10mg $65.00
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100mg $125.00
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  Pack size Price(USD)
50mg $95.00
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5g $225.00
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Exact Weight Packaging ($75(USD) / Vial)
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Inventory Status:   In Stock




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