trans-Abacavir-d4 Hydrochloride


Catalogue Number: A104997
Chemical Name: trans-Abacavir-d4 Hydrochloride
Synonyms: (1R,4R)-rel-4-[2-Amino-6-[cyclopropyl-d4)amino]-9H-purin-9-yl]-2-cyclopentene-1-methanol Hydrochloride; Abacavir Stable Isotope
CAS Number: 1346605-40-0
Alternate CAS #: 267668-71-3-unlabelled
Molecular Formula: C₁₄H₁₅D₄ClN₆O
Molecular Weight: 326.82
Category: Inhibitors, Isotope Labelled Compounds, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals
Applications: trans-Abacavir-d4 Hydrochloride is deuterium labeled trans-Abacavir Dihydrochloride (A104995), which is an impurity of Abacavir. Abacavir (A104990) is a carbocyclic 2’-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.
References:


All Products are stable to be shipped at room temperature, unless otherwise specified.
Product Rating
Keywords: Buy 1346605-40-0 | Purchase 1346605-40-0 | Order 1346605-40-0 | 1346605-40-0 supplier | 1346605-40-0 manufacturer | 1346605-40-0 distributor | 1346605-40-0 cost

Order Product

  Pack size Price(USD)
1mg $150.00
?
  Pack size Price(USD)
10mg $1200.00
?


Exact Weight Packaging ($75(USD) / Vial)
?
Inventory Status:   Currently Back Ordered - Please Request Lead Time

Add to Cart
?



Search Products:

Enter Catalogue #, CAS # , Chemical Name or Mol Formula:

Advance Search

Search By Category



Search By Parent Drug

Related Products

  • No Related Products

Alternate Products

Customers Also Viewed

Bulk Orders

If you require bulk orders or quantities you don't see listed, please click here

Translate »