Have a question about this product Click here.

All Products are stable to be shipped at room temperature, unless otherwise specified.
Pack Size Quantity Price (USD) Sub Total
1mg
$ 150.00 0.0
10mg
$ 775.00 0.0
25mg
$ 975.00 0.0
50mg
$ 1525.00 0.0
100mg
$ 2325.00 0.0
Exact Weight Packaging
$ 75.00 / Vial 0.0
Total $ 0.0
Request another packsize ? Click here.

Inventory Status : In Stock

Bulk Order Request for A104995

# Pack Size Unit Quantity
1.
2.
3.
4.
5.

Product Description

Catalogue Number: A104995
Chemical Name: trans-Abacavir Dihydrochloride
Synonyms: (1R,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol Diydrochloride;
Alternate CAS #: (HCl 1:1): 267668-71-3; 783292-37-5-free base
Molecular Formula: C₁₄H₂₀Cl₂N₆O
Appearance: Pale Yellow to Pale Orange Solid
Melting Point: >144°C (dec.)
Molecular Weight: 359.25
Storage: Refrigerator
Solubility: DMSO, Water (Slightly)
Category: Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications: trans-Abacavir Dihydrochloride is an impurity of Abacavir. Abacavir (A104990) is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.
References
Keywords: buy trans-Abacavir Dihydrochloride | Purchase trans-Abacavir Dihydrochloride | Order trans-Abacavir Dihydrochloride |
trans-Abacavir Dihydrochloride supplier | trans-Abacavir Dihydrochloride manufacturer | trans-Abacavir Dihydrochloride distributor | trans-Abacavir Dihydrochloride cost