Abacavir

Catalogue number: A104990
Chemical name: Abacavir
Synonyms: (1S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol; (1S-cis)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol; 1592U89; ABC; Abacavir API; Abacavir Impurities
Impurity: Abacavir API
CAS Number: 136470-78-5
Possible CAS #: NA
Molecular form.: C₁₄H₁₈N₆O
Appearance: Off-White Solid
Melting Point: 94-97°C
Mol. Weight: 286.33
Storage: Refrigerator
Solubility: DMSO (Slightly, Heated), Methanol (Slightly)
Stability: No Data Available
Category: Inhibitors, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Abacavir (Abacavir API) is a carbocyclic 2’-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.
Dangerous Goods Info: NA
References:

Peer Review Product Citations:
MSDS: A104990.pdf
Keywords: Buy 136470-78-5 | Purchase 136470-78-5 | Order 136470-78-5 | 136470-78-5 supplier | 136470-78-5 manufacturer | 136470-78-5 distributor | 136470-78-5 cost

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  Pack size Price(USD)
10mg $65.00
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500mg $175.00
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50mg $95.00
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250mg $150.00
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1g $225.00
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Exact Weight Packaging ($75(USD) / Vial)
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Inventory Status:   In Stock



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