A100185 Chemical Structure

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1mg
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10mg
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A100185

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Product Description

Catalogue NumberA100185
Chemical Name2-Amino-6-((2,6-dioxopiperidin-3-yl)carbamoyl)benzoic Acid
SynonymsPomalidomide Impurity
CAS Number1001852-14-7
Molecular FormulaC₁₃H₁₃N₃O₅
Molecular Weight291.26
Category Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications2-Amino-6-((2,6-dioxopiperidin-3-yl)carbamoyl)benzoic Acid is a metabolite of Pomalidomide, a thalidomide derivative, a potent inhibitor of TNF-α production. It is an antiinflammatory and antitumor agent used in the treatment of multiple myeloma.
ReferencesRuchelman, A. et al.: Bioorg. Med. Chem. Lett., 23, 360 (2013); Latif, T. et al.: Exp. Hematol. Oncol., 1, 27 (2012); Man, H. et al.: Bioorg. Med. Chem. Lett., 13, 3415 (2003); Muller, G. et al.: Bioorg. Med. Chem. Lett., 9, 1625 (1999)