Bromodomain Inhibitors are a class of antiviral drugs commonly used in the treatment of HIV. These molecules bind to regions of proteins known as bromodomains— which bind acetylated lysines in histone tails. Proteins that contain bromodomains are also epigenetic regulators, which play an important role in gene expression and regulation. This class of inhibitors blocks these protein interactions and in turn prevents viral replication within the host cell.
Discover our complete range of inhibitors and modulators along with building blocks, metabolites, impurities and labelled isotopes.
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