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|Product Name:||anti- ACC1 antibody|
|Storage:||PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)|
|Background:||ACACA(Acetyl-CoA carboxylase 1, ACC), also named as ACAC, ACC1 and ACCA, belongs to the biotin containing enzyme family. It catalyzes the synthesis of malonyl-CoA, which is an intermediate substrate playing a pivotal role in the regulation of fatty acid metabolism and energy production. ACACA is involved in the biosynthesis of fatty acids, and malonyl-CoA produced is used as a building block to extend the chain length of fatty acids by fatty acid synthase (FAS)(PMID:19900410). It has 4 isoforms produced by alternative promoter usage with the molecular weight between 260 kDa and 270 kDa.|
|Immunogen:||acetyl-Coenzyme A carboxylase alpha|
|Synonyms:||ACACA Synonyms ACAC, ACACA, ACC, ACC1, ACCA, Acetyl CoA carboxylase 1|
|Specificity:||Human, Mouse ,Rat|
|Tested Application:||ELISA, WB, IHC, IP, IF|
|Recommended Dilution:||WB :1:200-1:2000;IHC:1:20-1:200;IF:1:20-1:200;IP:1:200-1:2000|
|IHC Dilution:||Immunohistochemistry of paraffin-embedded human skeletal muscle using ACACA antibody at dilution of 1:50|
|WB Dilution:||HeLa cells were subjected to SDS PAGE followed by western blot with ACACA antibody at dilution of 1:500|