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|Product Name:||anti- ABCE1 antibody|
|Storage:||PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)|
|Background:||Antagonizes the binding of 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. May act as a chaperone for post-translational events during HIV-1 capsid assembly.|
|Immunogen:||ATP-binding cassette, sub-family E (OABP), member 1|
|Synonyms:||ABCE1, RLI, RNase L inhibitor, RNASEL1, OABP|
|Specificity:||human, Mouse , rat|
|Tested Application:||ELISA, WB, IHC|
|Recommended Dilution:||WB :1:500-1:5000;IHC:1:20-1:200|
|IHC Dilution:||Immunohistochemistry of paraffin-embedded human ovary tumor using ABCE1 antibody at dilution of 1:50|
|WB Dilution:||HEK-293 cells were subjected to SDS PAGE followed by western blot with ABCE1 antibody at dilution of 1:1500|