anti- AATF antibody



Catalogue number: AN00023
Product Name: anti- AATF antibody
Form: liquid
Host: Rabbit
Clonity: polyclonal
Isotope: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
Background: May function as a general inhibitor of the histone deacetylase HDAC1. Binding to the pocket region of RB1 may displace HDAC1 from RB1/E2F complexes, leading to activation of E2F target genes and cell cycle progression. Conversely, displacement of HDAC1 from SP1 bound to the CDKN1A promoter leads to increased expression of this CDK inhibitor and blocks cell cycle progression. Also antagonizes PAWR mediated induction of aberrant amyloid peptide production in Alzheimer disease (presenile and senile dementia), although the molecular basis for this phenomenon has not been described to date.
Immunogen: apoptosis antagonizing transcription factor
Synonyms: AATF, CHE 1, CHE1, DED, Protein AATF, Rb binding protein Che 1, Traube
Calculated MW: 63kDa
Uniport ID:
Specificity: Human, Mouse ,Rat
Tested Application: ELISA, WB, IF
Recommended Dilution: WB : 1:200-1:2000;IF:1:10-1:100
IHC Dilution:
WB Dilution: mouse brain tissue were subjected to SDS PAGE followed by western blot with AATF antibody at dilution of 1:800
Gene ID: 26574
Location: Nucleus
mouse brain tissue were subjected to SDS PAGE followed by western blot with AATF antibody at dilution of 1:800

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  Pack size Price(USD)
50μg $170.00
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100μg $245.00
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