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Product Description

Catalogue Number: AN00007
Product Name: anti- 5 Lipoxygenase antibody
Form: liquid
Host: Rabbit
Clonity: polyclonal
Isotope: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
Background: ALOX5(arachidonate 5-lipoxygenase) is also named as LOG5, 5-LO and belongs to the lipoxygenase family. It catalyzes the first step in leukotriene biosynthesis, and plays a role in inflammatory processes. It is a 78 kDa iron-containing enzyme that translocates from the cytosol to associate with FLAP, and converts arachidonate in two steps into the unstable intermediate LTA4. It is essential for cysteinyl-leukotriene (cys-LT) production, critical mediators in asthma(PMID:12911785).
Immunogen: arachidonate 5-lipoxygenase
Synonyms: 5 Lipoxygenase, 5 LO, 5 LOX, 5LPG, ALOX5, LOG5
Calculated MW: 75kDa
Specificity: Human, Mouse
Tested Application: ELISA, IF, WB
Recommended Dilution: WB : 1:200-1:2000;IF : 1:20-1:100
WB Dilution: HL-60 cells were subjected to SDS PAGE followed by western blot with ALOX5 Antibody at dilution of 1:600