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|Product Name:||anti- 15 Lipoxygenase 2 antibody|
|Storage:||PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20â„ƒ for 24 months (Avoid repeated freeze / thaw cycles.)|
|Background:||In humans, there are 6 functional lipoxygenases genes. Two of them encode for arachidonic acid 12-lipoxygenating (ALOX12, ALOX12B) and two for 15-lipoxygenating enzymes (ALOX15, ALOX15B). ALOX15B has been described as the most abundant 15-lipoxygenating enzyme species in human carotid atherosclerotic lesions and to be associated with cerebrovascular symptoms. (PMID:24373925). ALOX15B has 4?isoforms?produced by?alternative splicing with the MW of 76, 67, 69 and 73 kDa. 13073-1-AP can also recognize the mouse Alox8 protein.|
|Immunogen:||arachidonate 15-lipoxygenase, type B|
|Synonyms:||ALOX15B;Arachidonate 15-lipoxygenase B,15-LOX-B,15-LOX-2,Arachidonate 15-lipoxygenase type II,Linoleate 13-lipoxygenase 15-Lob|
|Specificity:||Human, Mouse ,Rat|
|Tested Application:||ELISA, WB, IHC,IF|
|Recommended Dilution:||WB : 1:200-1:2000;IHC : 1:20-1:200|
|IHC Dilution:||Immunohistochemistry of paraffin-embedded human prostate cancer using ALOX15B antibody at dilution of 1:100|
|WB Dilution:||MCF7 cells were subjected to SDS PAGE followed by western blot with ALOX15B antibody at dilution of 1:600|