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Product Description

Catalogue Number: AN00002
Product Name: anti- 14-3-3 antibody
Form: liquid
Host: Mouse
Clonity: monoclonal
Isotope: IgG1
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
Background: 14-3-3 theta (also known as YWHAQ, or 14-3-3 tau) is a member of 14-3-3 proteins which were the first phosphoserine/phosphothreonine-binding proteins to be discovered. 14-3-3 family members interact with a wide spectrum of proteins and possess diverse functions. Mammals express seven distinct 14-3-3 isoforms (gamma, epsilon, beta, zeta, sigma, theta, tau) that form multiple homo- and hetero- dimmers. 14-3-3 proteins display the highest expression levels in the brain, and have been implicated in several neurodegenerative diseases, including Alzheimer's disease and amyotrophic lateral sclerosis. This antibody was raised against full-length 14-3-3 theta.
Immunogen: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
Synonyms: 14-3-3 protein theta
Calculated MW: 28kDa
Specificity: Human, Rat
Tested Application: ELISA, WB, IHC, IF
Recommended Dilution: WB : 1:500-1:5000;IHC : 1:20-1:200;IF : 1:20-1:200
IHC Dilution: Immunohistochemistry of paraffin-embedded rat brain tissue slide using 14-3-3 Antibody at dilution of 1:50
WB Dilution: human brain tissue were subjected to SDS PAGE followed by western blot with 14-3-3 antibody at dilution of 1:1000