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|Product Name:||anti- 14-3-3 antibody|
|Storage:||PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20â„ƒ for 24 months (Avoid repeated freeze / thaw cycles.)|
|Background:||14-3-3 theta (also known as YWHAQ, or 14-3-3 tau) is a member of 14-3-3 proteins which were the first phosphoserine/phosphothreonine-binding proteins to be discovered. 14-3-3 family members interact with a wide spectrum of proteins and possess diverse functions. Mammals express seven distinct 14-3-3 isoforms (gamma, epsilon, beta, zeta, sigma, theta, tau) that form multiple homo- and hetero- dimmers. 14-3-3 proteins display the highest expression levels in the brain, and have been implicated in several neurodegenerative diseases, including Alzheimer's disease and amyotrophic lateral sclerosis. This antibody was raised against full-length 14-3-3 theta.|
|Immunogen:||tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide|
|Synonyms:||14-3-3 protein theta|
|Specificity:||Human, Mouse ,Rat|
|Tested Application:||ELISA, IF, IP, IHC, WB|
|Recommended Dilution:||WB : 1:1000-1:10000;IP : 1:200-1:2000;IHC : 1:20-1:200;IF : 1:20-1:200|
|IHC Dilution:||Immunohistochemistry of paraffin-embedded mouse brain tissue slide using 14-3-3 Antibody at dilution of 1:50|
|WB Dilution:||Hela cell were subjected to SDS PAGE followed by western blot with 14-3-3 Antibody at dilution of 1:3000|