ZM 447439

Catalogue number: Z487000
Chemical name: ZM 447439
Synonyms: N-[4-[[6-Methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]phenyl]benzamide;
CAS Number: 331771-20-1
Possible CAS #: NA
Molecular form.: C₂₉H₃₁N₅O₄
Appearance: Pale Yellow Solid
Melting Point: >104°C
Mol. Weight: 513.59
Storage: Refrigerator
Solubility: DMSO, Methanol
Stability: No Data Available
Category: Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: It is a potent and selective inhibitor of Aurora B kinase. Cells treated with ZM-447439 progress through interphase, enter mitosis and assemble bipolar spindles but chromosome alignment, segregation and cytokinesis all fail. It induces apoptosos in Hep2 cancer cells and in acute myeloid leukemia cell lines but its propensity to induce polyploidy does not inevitably result in apoptosis.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

Order Product

  Pack size Price(USD)
1mg $45.00
?
10mg $75.00
?
50mg $275.00
?
  Pack size Price(USD)
2mg $55.00
?
25mg $150.00
?
100mg $525.00
?
Exact Weight Packaging ($75(USD) / Vial)
?
Inventory Status:   In Stock

Search Products:

Enter Catalogue #, CAS # , Chemical Name or Mol Formula:

Search By Category

Search By Category View products by category
Translate »