Ziconotide Polyacetate

Catalogue number: Z385000
Chemical name: Ziconotide Polyacetate
Synonyms: ω-Conotoxin M VIIA Acetate; ω-Conopeptide MVIIA Acetate; Prialt Acetate; SNX 111;
CAS Number: 107452-89-1
Possible CAS #: 914454-03-8-for monoacetate; 107452-89-1 free pept
Molecular form.: C₁₀₂H₁₇₂N₃₆O₃₂S₇ •xC₂H₄O₂
Appearance: White Solid
Melting Point: >187°C (dec.)
Mol. Weight: 2639.13
Storage: Refrigerator
Solubility: DMSO (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Peptides, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Ziconotide, the peptide toxin of the Conus magus (cone snail) is a selective antagonist of N-type voltage sensitive calcium channels (VSCC). Blocks neurotransmitter release by preventing depolarization-induced calcium influx. Used as a ligand for binding studies of voltage sensitive calcium channels. Analgesic; neuroprotective.
Dangerous Goods Info: NA
References: Olivera, B.M., et al.: Biochemistry, 26, 2086 (1987), Barksdale, C.M., et al.: J. Clin. Ligand Assay, 19, 229 (1996), McGuire, D., et al.: J. Cardiovasc. Pharmacol., 30, 400 (1997), Staats, P.S., et al.: J. Am. Med. Assoc., 291, 63 (2004),
Peer Review Product Citations:

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  Pack size Price(USD)
.25mg $350.00
  Pack size Price(USD)
2.5mg $2800.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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