Catalogue number: Y100900
Chemical name: Yunnaconitine
Synonyms: (1α,3α,6α,14α,16β)-20-Ethyl-1,6,16-trimethoxy-4-(methoxymethyl)-8-acetate 14-(4-methoxybenzoate)aconitane-3,8,13,14-tetrol; Isoaconitine (6CI); Vilmorrianine B (7CI); 11aH-12,3,6a-Ethanylylidene-7,9-methanonaphth[2,3-b]azocine, Aconitane-3,8,13,14-tetrol Deriv.; 3α,13-Dihydroxyforesaconitine; Guayewuanine B; Yunaconitine;
CAS Number: 70578-24-4
Possible CAS #: NA
Molecular form.: C₃₅H₄₉NO₁₁
Appearance: White Solid
Melting Point: >128ºC (dec.)
Mol. Weight: 659.76
Storage: Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility: Chloroform (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Amines, Aromatics, Chiral Reagents, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Yunnaconitine is a metabolite of Aconitine (A189875), a neurotoxin that binds, activates tetrodotoxin-sensitive Na+ channels and prolongs the opening of the sodium-ion channel by suppressing conformational changes. Yunnaconitine is a deiterpene alkaloid, known to exhibit cytotoxic activity in human leukemic cell.
Dangerous Goods Info: NA
References: He, Y.Q., et al.: J. Pharma. Analysis., 1, 57 (2011); Derbre, S., et al.: Anal. Bioanal. Chem., 398, 1747 (2010); Li, M., et al.: J. Pharm. Biomed. Anal., 53, 1063 (2010);
Peer Review Product Citations:

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