XL388

Catalogue number: X746220
Chemical name: XL388
Synonyms: (7-(6-Aminopyridin-3-yl)-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)(3-fluoro-2-methyl-4-(methylsulfonyl)phenyl)methanone; [7-(6-Amino-3-pyridinyl)-2,3-dihydro-1,4-benzoxazepin-4(5H)-yl][3-fluoro-2-methyl-4-(methylsulfonyl)phenyl]-methanone
CAS Number: 1251156-08-7
Possible CAS #: NA
Molecular form.: C₂₃H₂₂FN₃O₄S
Appearance: Off-White to Pale Yellow Solid
Melting Point: >188ºC (dec.)
Mol. Weight: 455.5
Storage: Hygroscopic, Refrigerator, under inert atmosphere
Solubility: DMSO (Slightly)
Stability: No Data Available
Category: Amines, Aromatics, Inhibitors, Sulfur & Selenium Compounds
Boiling Point: No Data Available
Applications: XL388 is a highly potent, orally bioavailable, selective, ATP-competitive mammalian target of rapamycin (mTOR) inhibitor. XL388 has shown significant and dose-dependent antitumor activity in athymic nude mice implanted with human tumor xenografts.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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  Pack size Price(USD)
2.5mg $100.00
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10mg $220.00
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50mg $775.00
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  Pack size Price(USD)
5mg $150.00
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25mg $460.00
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Exact Weight Packaging ($75(USD) / Vial)
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Inventory Status:   In Stock

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