WYE-687

Catalogue number: W950005
Chemical name: WYE-687
Synonyms: Methyl 4-(4-morpholino-1-(1-(pyridin-3-ylmethyl)piperidin-4-yl)-1H-pyrazolo[3,4-d] pyrimidin-6-yl)phenylcarbamate Acid;
CAS Number: 1062161-90-3
Possible CAS #: NA
Molecular form.: C₂₈H₃₂N₈O₃
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 528.61
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amines, Aromatics, Heterocycles, Inhibitor, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: WYE-687 is an ATP-competitive and selective inhibitor of mammalian target of rapamycin (mTOR). Studies have shown the combination of Ras-Raf-MEK1/2 inhibitors with WYE-687 may overcome resistance to mTorKIs thus may be an effective additive therapy for treatment of patient with renal cell carcinoma or colorectal cancer.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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