Withaferin A

Catalogue number: W499200
Chemical name: Withaferin A
Synonyms: (4β,5β,6β,22R)-5,6-Epoxy-4,22,27-trihydroxy-1-oxoergosta-2,24-dien-26-oic Acid δ-Lactone; (20S,22R)-5,6β-Epoxy-4β,22,27-trihydroxy-1-oxo-5β-ergosta- 2,24-dien-26-oic Acid δ-Lactone; NSC 101088; NSC 273757; Withaferine; Withaferine A;
CAS Number: 5119-48-2
Possible CAS #: NA
Molecular form.: C₂₈H₃₈O₆
Appearance: White to Off-White Solid
Melting Point: 222-225°C
Mol. Weight: 470.6
Storage: -20˚C Freezer
Solubility: Chloroform (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Pharmaceuticals, Intermediates & Fine Chemicals, Steroids,
Boiling Point: No Data Available
Applications: Withaferin A is a promising anticancer constituent of Ayurvedic medicinal plant Withania somnifera. Withaferin A showed potent cytotoxicity against human head and neck squamous cell carcinoma (JMAR and MDA-1986). Withaferin A has recently been found to be a leptin sensitizer that can reduce the weight in obese mice fed in a high-fat diet (see C249500).
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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