Catalogue number: V678502
Chemical name: Voclosporin-d4
Synonyms: 6-[(2S,3R,4R,6E)-3-Hydroxy-4-methyl-2-(methylamino)-6,8-nonadienoic acid]cyclosporin A-d4; ISATX 247-d4; R 1524-d4; trans-ISA 247-d4;
CAS Number: NA
Possible CAS #: 515814-01-4-unlabelled
Molecular form.: C₆₃H₁₀₇D₄N₁₁O₁₂
Appearance: Off-White Solid
Melting Point: >129°C (dec.)
Mol. Weight: 1218.65
Storage: Amber Vial, -20°C Freezer, Under inert atmosphere
Solubility: Benzene (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Isotope Labelled Compounds, Peptides, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Labelled Voclosporin (V678500). A new agent for the treatment of noninfectious uveitis. Uveitis is an inflammatory, putative Th1-mediated autoimmune disease that affects various parts of the eye and is a leading cause of visual loss. Voclosporin, a rationally designed novel calcineurin inhibitor, exhibits a favorable safety profile, a strong correlation between pharmacokinetic and pharmacodynamic response, and a wide therapeutic window. Immunosuppressant.
Dangerous Goods Info: NA
References: Aspeslet, L., et al.: Transplant Proc., 33, 1048 (2001), Cho, M., et al.: Arthritis Rheum., 46, 1202 (2002), Staatz, C., et al.: Clin. Pharmacokinet., 43, 623 (2004),
Peer Review Product Citations:

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  Pack size Price(USD)
.5mg $175.00
2.5mg $700.00
10mg $2400.00
  Pack size Price(USD)
1mg $300.00
5mg $1325.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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