Vemurafenib

Catalogue number: V118500
Chemical name: Vemurafenib
Synonyms: N-[3-[[5-(4-Chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide; PLX 4032; RG 7204; Ro 51-85426;
CAS Number: 918504-65-1
Possible CAS #: NA
Molecular form.: C₂₃H₁₈ClF₂N₃O₃S
Appearance: Off-White Solid
Melting Point: >263ºC (dec.)
Mol. Weight: 489.92
Storage: Refrigerator
Solubility: DMSO (Slightly, Heated), Methanol (Slightly, Heated)
Stability: No Data Available
Category: Aromatics, Heterocycles, Protein Kinase Inhibitors and Activators, Sulfur & Selenium Compounds, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: Vemurafenib selective BRAFV600E kinase inhibitor; an antitumor agent. Vemurafenib functions by inhibiting the proliferation and mitogen-activated protein/extracellular signal-regulated kinase (ERK) kinase and ERK phosphorylation in a panel of tumor cell lines, including melanoma cell lines expressing BRAFV600E or other mutant BRAF proteins altered at codon 600.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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50mg $235.00
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Exact Weight Packaging ($75(USD) / Vial)
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Inventory Status:   In Stock

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