URB602

Catalogue number: U821925
Chemical name: URB602
Synonyms: Biphenyl-3-yl Carbamic Acid, Cyclohexyl Ester; N-[1,1’-Biphenyl]-3-yl-carbamic Acid Cyclohexyl Ester
CAS Number: 565460-15-3
Possible CAS #: NA
Molecular form.: C₁₉H₂₁NO₂
Appearance: Off-White Solid
Melting Point: 122-123°C
Mol. Weight: 295.38
Storage: No Data Available
Solubility: DMSO
Stability: No Data Available
Category: Aromatics, Inhibitors
Boiling Point: No Data Available
Applications: URB602 is a selective inhibitor of MGL, exhibiting an IC50 of 28 µM for the rat brain enzyme. It does not inhibit fatty acid amide hydrolase (FAAH) at concentrations up to 100 µM, or other lipid metabolizing enzymes such as diacylglycerol lipase or cyclooxygenase-2.5 6 Inhibition of 2-AG hydrolysis is associated with enhanced stress-induced analgesia and may represent a novel drug target in pain and stress management.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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