U-44069

Catalogue number: U100200
Chemical name: U-44069
Synonyms: (5Z)-7-[(1S,4R,5S,6R)-5-[(1E,3S)-3-Hydroxy-1-octen-1-yl]-2-oxabicyclo[2.2.1]hept-6-yl]-5-heptenoic Acid; (15S)-Hydroxy-9α,11α-(epoxymethano)prosta-5Z,13E-dienoic Acid; (5Z,9α,11α,13E,15S)-9,11-Epoxymethano-15-hydroxyprosta-5,13-dienoic Acid; 9,11-Dideoxy-9α,11α-epoxymethanoprostaglandin F2α; 9,11-Epoxymethano- prostaglandin H2; U 44069;
CAS Number: 56985-32-1
Possible CAS #: NA
Molecular form.: C₂₁H₃₄O₄
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 350.49
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Chiral Reagents, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: U-44069 is a stable analog of the endoperoxide PGH2, and a TP receptor agonist. U-44069 stimulates shape change in human platelets without a measurable increase in [Ca2+] with an EC50 of 1.8 nM. U-44069 has an EC50 of 3 µM and 54 nM for platelet aggregation and phosphatidate formation in human platelets, respectively.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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