N-Trifluoroacetyl-N-methyl-deacetylcolchiceine

Catalogue number: T789500
Chemical name: N-Trifluoroacetyl-N-methyl-deacetylcolchiceine
Synonyms: 2,2,2-Trifluoro-N-methyl-N-[(7S)-5,6,7,9-tetrahydro-10-hydroxy-1,2,3-trimethoxy-9-oxobenzo[a]heptalen-7-yl]acetamide;
CAS Number: 1217782-80-3
Possible CAS #: NA
Molecular form.: C₂₂H₂₂F₃NO₆
Appearance: Yellow Solid
Melting Point: No Data Available
Mol. Weight: 453.41
Storage: No Data Available
Solubility: Chloromethane, Dichlormethane, DMSO, Methanol
Stability: No Data Available
Category: Inhibitors
Boiling Point: No Data Available
Applications: An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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