N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride

Catalogue number: T788530
Chemical name: N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride
Synonyms: N-[4-[(4S)-2,5-Dioxo-4-oxazolidinyl]butyl]-2,2,2-trifluoroacetamide; (S)-N-[4-(2,5-Dioxo-4-oxazolidinyl)butyl]-2,2,2-trifluoroacetamide; Lys(Tfa)-NCA;
CAS Number: 42267-27-6
Possible CAS #: NA
Molecular form.: C₉H₁₁F₃N₂O₄
Appearance: White to Off-White Solid
Melting Point: 98-101°C
Mol. Weight: 268.19
Storage: -20˚C Freezer, Under Inert Atmosphere
Solubility: DMSO, Ethyl Acetate
Stability: No Data Available
Category: Amino Acids & Derivatives, Aromatics, Chiral Reagents, Heterocycles,
Boiling Point: No Data Available
Applications: Used in the synthesis of new arborescent architectures of poly(L-lysine), called lysine dendrigraft (DGL) polymers.  DGL polymers were prepd. through a multiple-generation scheme (up to generation 5) in a weakly acidic aq. medium by polycondensing N.vepsiln.-trifluoroacetyl-L-lysine-N-carboxyanhydride (Lys(Tfa)-NCA) onto the previous generation G(n-1) of DGL, which was used as a macroinitiator.  
Dangerous Goods Info: NA
References: Svenson, S., et al.: Adv. Drug Delivery Rev., 57, 2106 (2005), Shen, X., et al.: Org. Biomol. Chem., 5, 3674 (2007),
Peer Review Product Citations:

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Inventory Status:   Pending QC

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