N-Trifluoroacetyliso Deacetylcolchicine

Catalogue number: T788100
Chemical name: N-Trifluoroacetyliso Deacetylcolchicine
Synonyms: 2,2,2-Trifluoro-N-[(7S)-5,6,7,10-tetrahydro-1,2,3,9-tetramethoxy-10-oxobenzo[a]heptalen-7-yl]acetamide; N-(Trifluoroacetyl)deacetylisocolchicine;
CAS Number: 71324-48-6
Possible CAS #: NA
Molecular form.: C₂₂H₂₂F₃NO₆
Appearance: Tan Solid
Melting Point: 136-138˚C
Mol. Weight: 453.41
Storage: Refrigerator
Solubility: Chloroform, Dichlormethane, DMSO, Ethanol, Ethyl Acetate, Methanol
Stability: No Data Available
Category: Inhibitors
Boiling Point: No Data Available
Applications: An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.
Dangerous Goods Info: NA
References: Lunduena, R.F., et al.: Curr. Opin. Cell Biol., 4, 53 (1992), Ceccatelli, S., et al.: Neuroreport, 8, 3779 (1997), Want, T.H., et al.: J. Biol. Chem., 273, 4928 (1998), Andreu, J.M., et al.: Biochemistry, 37, 8356 (1998), Jordan, A., et al.: Med. Res. Rev., 18, 259 (1998),
Peer Review Product Citations:

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100mg $120.00
  Pack size Price(USD)
1g $960.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   Pending QC

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