Catalogue number: T774320
Chemical name: 2,4,5-Trichloropyrimidine
Synonyms: 2,4,5-Trichloropyrimidine; 2,5,6-Trichloropyrimidine; NSC 40593
CAS Number: 5750-76-5
Possible CAS #: NA
Molecular form.: C₄HCl₃N₂
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 183.42
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Heterocycles, Miscellaneous Reagents
Boiling Point: No Data Available
Applications: 2,4,5-Trichloropyrimidine is used in the synthesis of potent and selective anaplastic lymphoma kinase (ALK-5) inhibitors, used as an anti-tumor treatment. Also used in the synthesis of EGFR inhibitors.
References: Marsilje, T. et al.: J. Med. Chem., 56, 5675 (2013); Park, C. et al.: Bioorg. Med. Chem. Lett., 23, 6192 (2013); Han, C. et al.: Eur. J. Med. Chem., 66, 82 (2013);
Dangerous Goods Info: NA

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