N4,3’,5’-Tribenzoyl,2’-deoxy-2’β-fluoro-2’C-α-methyl Cytidine

Catalogue number: T767675
Chemical name: N4,3’,5’-Tribenzoyl,2’-deoxy-2’β-fluoro-2’C-α-methyl Cytidine
Synonyms: (2R,3R,4S,5R)-5-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4-fluoro-4-methyltetrahydrofuran-3-yl Benzoate
CAS Number: NA
Possible CAS #: NA
Molecular form.: C₃₁H₂₆FN₃O₇
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 571.55
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: No Data Available
Boiling Point: No Data Available
Applications: N4,3’,5’-Tribenzoyl,2’-deoxy-2’β-fluoro-2’C-α-methyl Cytidine is an impurity of Sofosbuvir (P839640); a prodrug that is metabolized to the active antiviral agent 2’-deoxy-2’-α-fluoro-β-C-methyluridine-5’-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled Sofosbuvir as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.
Dangerous Goods Info: NA
References: Lam, A.M.,et al.: Antimicrob. Agents. Chemotherapy., 56, 3359 (2012); Lam, A.M., et al.: J. Virol., 85, 12334 (2011); Sofia, M.J., et al.: J. Medn. Chem., 53, 7202 (2010)
Peer Review Product Citations:

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  Pack size Price(USD)
1mg $190.00
10mg $1675.00
  Pack size Price(USD)
5mg $875.00
Exact Weight Packaging ($75(USD) / Vial)
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