Catalogue number: T767420
Chemical name: 1,2,4-Triazol-4-amine
Synonyms: 4-Amino-4H-1,2,4-triazole; 1,2,4-Triazol-4-ylamine; 1,2,4-Triazole-4-amine; 1-Amino-1,3,4-triazole; 1-Amino-1H-1,3,4-triazole; 4-Amino-1,2,4(4H)-triazole; 4-Amino-1,2,4-triazole; 4-Amino-4H-1,2,4-triazole; NSC 3263; NSC 7242
CAS Number: 584-13-4
Possible CAS #: NA
Molecular form.: C₂H₄N₄
Appearance: Off-White Solid
Melting Point: 74-79ºC
Mol. Weight: 84.08
Storage: Refrigerator, under inert atmosphere
Solubility: DMSO (Sparingly), Methanol (Slightly)
Stability: No Data Available
Category: Amines, Heterocycles, Miscellaneous Reagents
Boiling Point: No Data Available
Applications: 1,2,4-Triazol-4-amine is an intermediate used to prepare potent, selective, and orally active cyclooxygenase-​2 inhibitors. It is also used to synthesize hydroxyphenacyl azoles and related azolium derivatives as antifungal agents.
Dangerous Goods Info: NA
References: Song, Y., et al.: J. Med. Chem., 42, 1151 (1999); Emami, S., et al.: Bioorg. Med. Chem. Lett., 18. 141 (2008)
Peer Review Product Citations:

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