Catalogue number: T712602
Chemical name: Trametinib-d4
Synonyms: N-[3-[3-Cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]acetamide-d4; G 02442104-d4; GSK 1120212-d4; JTP 74057-d4
CAS Number: NA
Possible CAS #: Unlabelled: 871700-17-3 (C988930)
Molecular form.: C₂₆H₁₉D₄FIN₅O₄
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 619.42
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amines, Aromatics, Heterocycles, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Trametinib-d4 is the isotope labelled analog of Trametinib (C988930); a compound used in the systematic treatment of advanced cutaneous melanoma. Trametinib is also an EGFR kinase inhibitor.
Dangerous Goods Info: NA
References: Ercan, D. et al.: Canc. Disc., 2, 934 (2012); Mackiewicz-Wysocka, M. et al.: Exp. Opin. Investig. Drugs., 22, 181 (2013)
Peer Review Product Citations:

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