Tosedostat-d5

Catalogue number: T549002
Chemical name: Tosedostat-d5
Synonyms: (αS)-α-[[(2R)-2-[(1S)-1-Hydroxy-2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]amino]benzeneacetic Acid-d5 Cyclopentyl Ester; CHR 2797-d5;
CAS Number: 1217844-03-5
Possible CAS #: NA
Molecular form.: C₂₁H₂₅D₅N₂O₆
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 411.5
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amines, Aromatics, Chiral Reagents, Inhibitors, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Labelled Tosedostat. CHR-2797 is a novel metalloenzyme inhibitor that is converted into a pharmacological active acid product (CHR-79888) inside cells. CHR-2797 exerts antiproliferative effects against a range of tumor cell lines in vitro and in vivo and shows selectivity for transformed over nontransformed cells. Its antiproliferative effects are at least 300 times more potent than the prototypical aminopeptidase inhibitor, Bestatin.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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