Catalogue number: T549000
Chemical name: Tosedostat
Synonyms: (αS)-α-[[(2R)-2-[(1S)-1-Hydroxy-2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]amino]benzeneacetic Acid Cyclopentyl Ester; CHR 2797;
CAS Number: 238750-77-1
Possible CAS #: NA
Molecular form.: C₂₁H₃₀N₂O₆
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 406.47
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amines, Aromatics, Chiral Reagents, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: CHR-2797 is a novel metalloenzyme inhibitor that is converted into a pharmacological active acid product (CHR-79888) inside cells. CHR-2797 exerts antiproliferative effects against a range of tumor cell lines in vitro and in vivo and shows selectivity for transformed over nontransformed cells. Its antiproliferative effects are at least 300 times more potent than the prototypical aminopeptidase inhibitor, Bestatin.
Dangerous Goods Info: NA
References: Sato, Y., et al.: Biol. Pharm. Bull., 27, 772 (2004), Saveanu, L., et al.: Nat. Immunol., 6, 689 (2005), Proud, C., et al.: Biochem. J., 403, 217 (2007), Watatani, Y., et al.: Life Sci., 80, 879 (2007),
Peer Review Product Citations:

Order Product

  Pack size Price(USD)
10mg $150.00
  Pack size Price(USD)
100mg $1200.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   Please Inquire

Search Products:

Enter Catalogue #, CAS # , Chemical Name or Mol Formula:

Search By Category

Search By Category View products by category
Translate »