Torin 1

Catalogue number: T548700
Chemical name: Torin 1
Synonyms: 1-[4-[4-(1-Oxopropyl)-1-piperazinyl]-3-(trifluoromethyl)phenyl]-9-(3-quinolinyl)benzo[h]-1,6-naphthyridin-2(1H)-one;
CAS Number: 1222998-36-8
Possible CAS #: NA
Molecular form.: C₃₅H₂₈F₃N₅O₂
Appearance: White to Off-Wite Solid
Melting Point: >223°C (dec.)
Mol. Weight: 607.62
Storage: -20˚C Freezer
Solubility: Chloroform, DMSO, Methanol (Sparigly)
Stability: No Data Available
Category: Amines, Aromatics, Heterocycles, Pfizer Compounds, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Torin 1 is a potent and selective mTOR inhibitor (IC50 = 2 - 10 nM for mTORC1 and mTORC2). Displays 200-fold selectivity for mTOR over DNA-PK, ATM and hVps34.
Dangerous Goods Info: NA
References: Thoreen, et al.: J. Biol. Chem., 284, 8023 (2009), Liu, et al.: J. Med. Chem., 53, 7146 (2010), Peterson, et al.: Peterson, et al.: Cell, 146 408 (2011),
Peer Review Product Citations:

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  Pack size Price(USD)
10mg $110.00
50mg $425.00
  Pack size Price(USD)
25mg $245.00
100mg $795.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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