(S)-Topotecan

Catalogue number: T542495
Chemical name: (S)-Topotecan
Synonyms: (S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3’,4’:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; Topotecan; 10-Hydroxy-9-[(dimethylamino)methyl]-(20S)-camptothecin; 9-(N,N-Dimethylaminomethyl)-10-hydroxycamptothecin; Hycamptamine; Hycamptin; NSC 609699; Nogitecan; SKF 104864; SKF-S 104864; TopoCED; Topophore C; Topotecan Lactone
CAS Number: 123948-87-8
Possible CAS #: NA
Molecular form.: C₂₃H₂₃N₃O₅
Appearance: Yellow Solid
Melting Point: >155°C (dec.)
Mol. Weight: 421.45
Storage: -20°C Freezer
Solubility: Aqueous Acid (Slightly, Heated), DMSO (Slightly)
Stability: No Data Available
Category: Chiral Reagents, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: (S)-Topotecan is a DNA topoisomerase I inhibitor; semisynthetic analog of Camptothecin. Antineoplastic. Topotecan hydrochloride is a chemotherapy agent that is a topoisomerase 1 inhibitor.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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