Catalogue number: T542490
Chemical name: (R)-Topotecan
Synonyms: (4R)-10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3’,4’:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
CAS Number: 1797985-73-9
Possible CAS #: S-isomer: 123948-87-8
Molecular form.: C₂₃H₂₃N₃O₅
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 421.45
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: No Data Available
Boiling Point: No Data Available
Applications: (R)-Topotecan is the R-isomer of Topotecan (T542495); a DNA topoisomerase I inhibitor and semisynthetic analog of Camptothecin. Also antineoplastic.
Dangerous Goods Info: NA
References: Beijnen, J.H., et al.: J. Pharm. Biomed. Anal., 8, 789 (1990); BeiKingsburg, W.D., et al.: J. Med. Chem., 34, 98 (1991); Rowinsky, E.K., et al.: J. Clin. Oncol., 10, 647 (1992)
Peer Review Product Citations:

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