α-Tocopheryl Succinate

Catalogue number: T539950
Chemical name: α-Tocopheryl Succinate
Synonyms: CV 104; Covitol 1210; NSC 173849; d-α-Tocopherol Acid Succinate; Butanedioic Acid 1-[(2R)-3,4-Dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-yl] Ester; (+)-2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)-6-chromanol Hydrogen Succinate; d-α-Tocopheryl Acid Succinate; (+)-α-Tocopheryl Succinate; Succinic Acid (+)-mono[2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-6-chromanyl] ester; α-Vitamin E Succinate; Vitamin E d-α-Tocosuccinate;
CAS Number: 4345-03-3
Possible CAS #: NA
Molecular form.: C₃₃H₅₄O₅
Appearance: Off-White to Pale Yellow Solid
Melting Point: 75-77°C
Mol. Weight: 530.78
Storage: Refrigerator
Solubility: Chloroform (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Aromatics, Chiral Reagents, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: A potent novel antineoplastic agent with high selectivity and cooperativity with tumor necrosis factor-related apoptosis-inducing ligand (Apo2 ligand). It inhibits proliferation of mesothelioma cells by selective down-regulation of fibroblast growth factor receptors. Furthermore, it has been shown to enhance the anti-tumor effect of dendritic cell vaccines.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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