Catalogue number: T528012
Chemical name: (3S,4R)-Tofacitinib-d3
Synonyms: (3S,4R)- 4-Methyl-3-(methyl-d3-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-β-oxo-1-piperidinepropanenitrile; 2-Isocyano-1-((3S,4R)-4-methyl-3-(methyl-d3(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)ethanone
CAS Number: NA
Possible CAS #: unlabeled: 1092578-48-7
Molecular form.: C₁₆H₁₇D₃N₆O
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 315.39
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amines, Aromatics, Chiral Reagents, Inhibitors, Isotope Labelled Compounds
Boiling Point: No Data Available
Applications: (3S,4R)-Tofacitinib-d3 is the labeled analogue of (3S,4R)-Tofacitinib (T528010), an enantiopure stereoisomer of the drug, Janus kinase 3(Jak3) inhibitor (CP-690,550) that has been found to inhibit selected members of the STE7 and STE20 subfamily of kinases.
Dangerous Goods Info: NA
References: Jiang, J., et. al.: J. med. Chem., 51, 8012 (2008)
Peer Review Product Citations: Jiang, J., et. al.: J. med. Chem., 51, 8012 (2008)

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