Catalogue number: T525500
Chemical name: Toceranib
Synonyms: 5-[(Z)-(5-Fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-N-[2-(1-pyrrolidinyl)ethyl]-1H-pyrrole-3-carboxamide; 5-(5-Fluoro-2-oxo-1,2-dihydroindol-(3Z)-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid (2-(Pyrrolidin-1-yl)ethyl)amide; PHA 291639; SU 11654;
CAS Number: 356068-94-5
Possible CAS #: NA
Molecular form.: C₂₂H₂₅FN₄O₂
Appearance: Dark Yellow Solid
Melting Point: >133°C (dec.)
Mol. Weight: 396.46
Storage: Refrigerator
Solubility: DMSO (Slightly, Heated), Methanol (Very Slightly, Heated)
Stability: No Data Available
Category: Aromatics, Heterocycles, Indole Derivatives, Pfizer Compounds, Pharmaceuticals, Intermediates & Fine Chemicals, Tyrosine Kinase Inhibitors,
Boiling Point: No Data Available
Applications: Toceranib is a multitargeted indolinone receptor tyrosine kinase (RTK) inhibitor. Toceranib exhibited activity against a variety of spontaneous malignancies in canine such as mast cell tumors, mixed mammary carcinomas, soft tissue sarcomas, and multiple myeloma.
Dangerous Goods Info: NA
References: London, C.A. et al.: Clin. Cancer Res., 9, 2755 (2003); Zavodovskaya, R. et al.: Am. J. vVt. Res., 67, 633 (2006); Malone, E.K. et al.: Vet. Comp. Oncol., 8, 209 (2010);
Peer Review Product Citations:

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50mg $875.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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