Catalogue number: T425602
Chemical name: Thyroxine-13C6
Synonyms: O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine; (-)-Thyroxine; 3,3’,5,5’-Tetraiodo-L-thyronine; Henning; L-T4; L-Thyroxin; Levothyroxine; NSC 36397; T4; T4 (hormone); Thyrax; Thyreoideum; Thyroxin; Thyroxinal;
CAS Number: 1217780-14-7
Possible CAS #: unlabelled: 51-48-9
Molecular form.: C₉¹³C₆H₁₁I₄NO₄
Appearance: White to Pale Beige Solid
Melting Point: >125˚C (dec.)
Mol. Weight: 782.83
Storage: -20°C Freezer, Under Inert Atmosphere
Solubility: DMSO (Slightly), Methanol (Very Slightly)
Stability: No Data Available
Category: Amino Acids & Derivatives, Aromatics, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: One of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH). Deiodinated in peripheral tissues to the active metabolite, liothyronine. The D-form has very little activity as a thyroid hormone, but has been used to treat hyperlipidemia.
Dangerous Goods Info: NA
References: Post, A., et al.: Anal. Profiles Drug Subs., 5, 225 (1976), Nelson, J.C., et al.: Clin. Chem., 34, 1737 (1988), Fischer, D.A., et al.: Clin. Chem., 42, 135 (1996), Cavalieri, R.R., et al.: Thyroid, 7, 177 (1997),
Peer Review Product Citations:

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