TH-302-d8

Catalogue number: T338202
Chemical name: TH-302-d8
Synonyms: N,N’-Bis(2-bromoethyl)phosphorodiamidic Acid-d8 (1-Methyl-2-nitro-1H-imidazol-5-yl)methyl Ester;
CAS Number: 918632-75-4
Possible CAS #: NA
Molecular form.: C₉H₈D₈Br₂N₅O₄P
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 457.09
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Heterocycles, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: TH-302-d8 is the isotope labelled analog of TH-302 (T338200), a 2-nitroimidazole triggered hypoxia-activated prodrug (HAP) of bromo-isophosphoramide mustard. Studies have shown that TH-302 treatment exhibited hypoxia-selective cytotoxicity and DNA damage in human cancer cell.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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