Catalogue number: T305785
Chemical name: Tetrandrine
Synonyms: (4aS,16aS)-3,4,4a,5,16a,17,18,19-octahydro-12,21,22,26-tetramethoxy-4,17-dimethyl-16H-1,24:6,9-Dietheno-11,15-metheno-2H-pyrido[2’,3’:17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinoline;
CAS Number: 518-34-3
Possible CAS #: NA
Molecular form.: C₃₈H₄₂N₂O₆
Appearance: Off-White Solid
Melting Point: >190°C (dec.)
Mol. Weight: 622.75
Storage: Refrigerator
Solubility: Chloroform (Slightly), Methanol (Slightly, Heated)
Stability: No Data Available
Category: Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Tetrandrine is a lipopolysaccharide-induced microglial suppressor, effectively reducing the production of bacterial inflammatory mediators. Anti-inflammatory, anti-nociceptive. Tetrandrine is used in China to treat high blood pressure. This drug blocked the TPC2 calcium channel required for the Ebola infection process (Robert A. Davey et al., Science 2015, DOI: 10.1126/science.1258758).
Dangerous Goods Info: NA
References: Yalong, D. et al.: PLoS One. 9, e102522 (2014); Westra, I. et al.: PLoS One., 9, e95462 (2014); Chem. and Eng. News, 93 (9) 8 Mar.2 (2015)
Peer Review Product Citations:

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