Catalogue number: T294265
Chemical name: 5,6,7,8-Tetrahydro-1-naphthalenol
Synonyms: 1,2,3,4-Tetrahydro-5-hydroxynaphthalene; 1,2,3,4-Tetrahydro-5-naphthol; 1,2,3,4-Tetrahydronaphthalen-5-ol; 1-Hydroxy-5,6,7,8-tetrahydronaphthalene
CAS Number: 529-35-1
Possible CAS #: NA
Molecular form.: C₁₀H₁₂O
Appearance: Pale Orange Solid
Melting Point: 67-69°C
Mol. Weight: 148.2
Storage: Refrigerator
Solubility: Chloroform (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: No Data Available
Boiling Point: No Data Available
Applications: 5,6,7,8-Tetrahydro-1-naphthalenol was used as a reagent in the synthesis of phosphonamidate and phosphonodiamidate prodrugs of adefovir and tenofovir which are used in the treatment of HIV infections. Also used in the synthesis of tetrahydronaphthalene-1-ol derivatives which were found to be promising potent antitumor agents.
Dangerous Goods Info: NA
References: Pertusati, F., et al.: Eur. J. Med. Chem., 78, 259 (2014); Dong, Y., et al.: Bioorg. Med. Chem. Lett., 19, 6289 (2009);
Peer Review Product Citations:

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