Catalogue number: T007600
Chemical name: Tariquidar
Synonyms: N-[2-[[[4-[2-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]amino]carbonyl]-4,5-dimethoxyphenyl]-3-quinolinecarboxamide; XR 9576
CAS Number: 206873-63-4
Possible CAS #: NA
Molecular form.: C₃₈H₃₈N₄O₆
Appearance: Pale Yellow Solid
Melting Point: >204°C (dec.)
Mol. Weight: 646.73
Storage: Refrigerator
Solubility: Chloroform, DMSO
Stability: No Data Available
Category: Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Tariquidar is a p-glycoprotein drug efflux pump inhibitor. Tariquidar inhibits the ATPase activity of P-glycoprotein, suggesting that the modulating effect is derived from the inhibition of substrate binding, inhibition of ATP hydrolysis or both.Tariquidar can be considered an ideal agent for testing the role of P-glycoprotein inhibition in cancer.
Dangerous Goods Info: NA
References: Fox, E., et al.: Expert. Rev. Ainticancer. Ther., 7, 447 (2007); Hernandez, D., et al.: Biochem. Pharmacol., 85, 21 (2013); Bauer, F., et al.: Euro. J. Pharmacol., 696, 18 (2012);
Peer Review Product Citations:

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50mg $450.00
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25mg $265.00
100mg $750.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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