Talmapimod

Catalogue number: T005550
Chemical name: Talmapimod
Synonyms: 6-Chloro-5-[[(2R,5S)-4-[(4-fluorophenyl)methyl]-2,5-dimethyl-1-piperazinyl]carbonyl]-N,N,1-trimethyl-α-oxo-1H-indole-3-acetamide; SCIO 469; Scios 469;
CAS Number: 309913-83-5
Possible CAS #: NA
Molecular form.: C₂₇H₃₀ClFN₄O₃
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 513
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Heterocycles, Indole Derivatives, Pharmaceuticals, Intermediates & Fine Chemicals, Protein Kinase Inhibitors and Activators,
Boiling Point: No Data Available
Applications: Talmapimod is a p38 mitogen-activated protein (MAP) kinase inhibitor. Talmapimod reduced human myeloma cell growth in vivo both at early and advanced phases of the disease in mouse xenograft models. Talmapimod that blocks tumor necrosis factor-α, interleukin-1β, and cyclooxygenase-2 synthesis in patients with active rheumatoid arthritis (RA)
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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