Catalogue number: T004922
Chemical name: TAK-901-d3
Synonyms: 5-[3-(Ethylsulfonyl)phenyl]-3,8-dimethyl-N-(1-methyl-4-piperidinyl)-9H-pyrido[2,3-b]indole-7-carboxamide;
CAS Number: 1346603-28-8
Possible CAS #: 934541-31-8 unlabelled
Molecular form.: C₂₈H₂₉D₃N₄O₃S
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 507.66
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Heterocycles, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals, Protein Kinase Inhibitors and Activators, Sulfur & Selenium Compounds,
Boiling Point: No Data Available
Applications: A labelled novel Aurora B kinase inhibitor with potential antineoplastic activity. It binds to and inhibits the activity of Aurora B, which may result in a decrease in the proliferation of tumor cells that overexpress Aurora B. Aurora B is a positive regulator of mitosis that functions in the attachment of the mitotic spindle to the centromere; the segregation of sister chromatids to each daughter cell; and the separation of daughter cells during cytokinesis.
Dangerous Goods Info: NA
Peer Review Product Citations:

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