Catalogue number: T004905
Chemical name: rac-TAK-875
Synonyms: 6-[[2’,6’-Dimethyl-4’-[3-(methylsulfonyl)propoxy][1,1’-biphenyl]-3-yl]methoxy]-2,3-dihydro-3-benzofuranacetic Acid
CAS Number: 1390641-84-5
Possible CAS #: R-isomer: 1234474-57-7; S-isomer: 1000413-72-8
Molecular form.: C₂₉H₃₂O₇S
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 524.63
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
Boiling Point: No Data Available
Applications: rac-TAK-875 is a potent, selective, and orally bioavailable GPR40 agonist. It also inspired the synthesis of the novel FFA1 agonist TUG-469 for the treatment of type 2 diabetes.
Dangerous Goods Info: NA
References: Negoro, N., et al.: ACS Med. Chem. Lett., 1, 290 (2010); Christiansen, E., et al.: J. Med. Chem., 55, 6624 (2012)
Peer Review Product Citations:

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