Sulindac Sulfide-d6 (Major)

Catalogue number: S699222
Chemical name: Sulindac Sulfide-d6 (Major)
Synonyms: (Z)-5-Fluoro-2-methyl-1-[p-(methylthio)benzylidene]indene-3-acetic Acid-d6;
CAS Number: NA
Possible CAS #: NA
Molecular form.: C₂₀H₁₁D₆FO₂S
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 346.45
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Isotope Labelled Compounds, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
Boiling Point: No Data Available
Applications: Labelled analogue of Sulindac Sulfide, an active metabolite of Sulindac. Inhibits cyclooxygenase, but induces apoptosis by a cyclooxygenase-independent mechanism. Inhibition of Ras activation of Ref-1. Impairs nucleotide exchange on Ras by CDC25 and accelerates Ras hydrolysis of GTP by p120GAP.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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