Suberoyl Bis-hydroxamic Acid

Catalogue number: S688750
Chemical name: Suberoyl Bis-hydroxamic Acid
Synonyms: N1,N8-Dihydroxyoctanediamide; N,N’-Dihydroxyoctanediamide; SBHA; Suberodihydroxamic Acid; Suberic Bishydroxamate;
CAS Number: 38937-66-5
Possible CAS #: NA
Molecular form.: C₈H₁₆N₂O₄
Appearance: White to Light Beige Solid
Melting Point: 154-156°C
Mol. Weight: 204.22
Storage: Hygroscopic, Refrigerator, under inert atmosphere
Solubility: DMSO, Methanol
Stability: No Data Available
Category: Amines, Aromatics, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Histone deacetylase inhibitor. A cell-permeable inhibitor of HDAC1 and HDAC3. Shown to suppresses the growth of proliferating keratinocytes and squamous cell carcinoma cells.
Dangerous Goods Info: NA
References: Marks, P.A., et al.: Proc.Natl. acad. Sci., 91, 10251 (1994), Brinkmann, H., et al.: J. Biol. Chem., 276, 22491 (2001), Haupt, S., et al.: J. Cell Sci., 116, 4077 (2003), Zhang, X., et al.: Biochem. Pharmacol., 66, 1537 (2003), Crighton, D., et al.: Biochim. Biophys Acta, 1705, 3 (2004),
Peer Review Product Citations:

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500mg $55.00
2.5g $125.00
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250mg $50.00
1g $60.00
25g $1120.00
Exact Weight Packaging ($75(USD) / Vial)
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