Catalogue number: S684470
Chemical name: SSR128129E
Synonyms: 2-Amino-5-[(1-methoxy-2-methyl-3-indolizinyl)carbonyl]-benzoic Acid Sodium Salt; 2-Amino-5-[(1-methoxy-2-methyl-3-indolizinyl)carbonyl]-benzoic Acid Monosodium Salt; SSR 128129E; Sodium 2-Amino-5-[(1-methoxy-2-methylindolizin-3-yl)carbonyl]benzoate
CAS Number: 848318-25-2
Possible CAS #: NA
Molecular form.: C₁₈H₁₅N₂NaO₄
Appearance: Yellow Solid
Melting Point: >238°C (dec.)
Mol. Weight: 346.31
Storage: Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility: DMSO (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Amines, Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: SSR128129E (SSR) is an potent FGFR inhibitor, which inhibits fibroblast growth factor receptor (FGFR). Oral delivery of SSR128129E inhibits arthritis and tumors that are relatively refractory to anti-vascular endothelial growth factor receptor-2 antibodies.
Dangerous Goods Info: NA
References: Bono, F., et al.: Cancer Cell., 23, 477 (2013); Dol-Gleizes, F., et al.: PLoS One, 8, e80027 (2013)
Peer Review Product Citations:

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  Pack size Price(USD)
5mg $110.00
100mg $825.00
  Pack size Price(USD)
25mg $250.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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