SRT 1460-d9

Catalogue number: S684452
Chemical name: SRT 1460-d9
Synonyms: 3,4,5-Trimethoxy-N-[2-[3-(1-piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl]phenyl]-benzamide-d9
CAS Number: NA
Possible CAS #: 925432-73-1 unlabelled
Molecular form.: C₂₆H₂₀D₉N₅O₄S
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 516.66
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amines, Aromatics, Heterocycles, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: SRT 1460-d9 is labelled SRT 1460 (S684450), a drug intended as a small-molecule activator of the sirtuin subtype SIRT1. it was found to improve insulin sensitivity and lower plasma glucose levels in fat, muscle and liver tissue, and increased mitochondrial and metabolic function.
Dangerous Goods Info: NA
References: Milne, J., et al.: Nature, 450, 712 (7170); Pacholec, M., et al.: J. BIol. Chem., 285, 8340 (2010); Dai, H., et al.: J. Biol. Chem., 285, 32695 (2010)
Peer Review Product Citations:

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